Abstract. Nutr Cancer. Recent studies: There are also recent studies done about Muntingia Calabura Linn. Other than the Kerson fruit itself, it is also worth mentioning the … ABSTRACT The present investigation, describes the phytochemical analysis, in vitro antioxidant and antidiabetic property of Muntingia calabura leaves extracts along with estimate the inorganic components of the leaves. Jisha N; Vysakh A; Vijeesh V; Anand PS; Latha MS. Context: Different parts of Muntingia calabura L. (Elaeocarpaceae), or “kerukup siam” in Malay, have been reported to possess medicinal value, supported by a number of scientific studies.. The plant is native to southern Mexico, Central America, tropical South America, the Greater Antilles, St. Vincent and Trinidad. The inorganic components present in the leaves were estimated by Narendhirakannan method. Safety evaluation of orally-administered methanol extract of Muntingia calaburaLinn. Soft drinks induction causes liver injuries which increases the serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) levels. Muntingia calabura L., locally known as kersen, traditionally has been used to control blood glucose level. Objective: This study aimed to determine the cytotoxic activity of the methanolic extract of Muntingia calabura leaves against A549 Human lung adenocarcinoma cell line. The result showed that M. calabura leaves contain secondary metabolites, one of which was condensed tannins detected in this study. Keywords Elaeocarpaceae, ethnomedicinal uses, Another study on the antiulcer potential of M. calabura leaves was studied. M. calabura is planted as a source of timber and fuel. Muntingia calabura L is a flowering plant native to southern mexico, central america, Caribbean, western to south America. The purpose of this study was to determine the effectiveness of boiled cherry leaves (muntingia calabura L) and Figs leaves (Ficus Carica) to reduce SGOT SGPT levels. The timber of Jamaican cherry is reddish-brown, compact, durable, light weight and used in carpentry, firewood. The bark gives ropes and fiber for bark skirts. It is commonly known as the Jamaican cherry in Brazil and ‘Kerukup Siam’ in Asian region, including Malaysia. This study aimed to analyse the antioxidant activity, total phenols, and flavonoids of kersen leaves (Muntingia calabura L.) extract (KLE) and determine the hepatoprotective activity of KLE in soft drink induced mice. (5) Previous studies suggested Muntingia calabura as a great source of flavonoids which act as potent antioxidant agents, with the highest content of flavonoids lay within its leaves. Last January 2008, the leaves have been previously identified by a botanist at University Putra Malaysia (UPM) Serdang Selangor, and a voucher specimen (SK 964/04) has been preserved at the Herbarium of the laboratory of Natural product, Institute of Bioscience, UPM, Selangor, Malaysia. Fruit from Muntingia is also harvested for export overseas. Following on these folklore claims, the works on phytochemicals constituents, traditional uses, pharmacological benefits and their mechanisms are presented in a number of studies as well as the in vitro and in vivo investigations. Muntingia calabura L. leaves were therapeutically used for ulcer, fever, headache etc. Abstract. While, it was not significantly different from albendazole 2 mg/ml on EHI test. Reduces Inflammation. Kerson Fruit for a Healthy Heart. ''Muntingia calabura'' is a shrub or tree up to 12 m tall with spreading branches. Insecticidal activity of Muntingia calabura extracts against larvae and pupae of diamondback, Plutella xylostella (Lepidoptera, Plutellidae). Its soft wood used for rural construction, while the bark is fibrous and used for making ropes. The present study investigates the qualitative and quantitative analysis of the major bioactive constituents of plant Muntingia calabura in some solvents … View This Abstract Online; Methanolic Extract of Muntingia Calabura L. Mitigates 1,2-Dimethyl Hydrazine Induced Colon Carcinogenesis in Wistar Rats. The fruits are edible and in some cases sold in markets, as they can be eaten raw or processed as jam; leaves can be used for making tea. such as Indonesia. leaves: A sub-chronic toxicity study in Sprague Dawley rats Nur Liana Md Nasir1, Noorsyaza Eddrina Kamsani1, Norhafizah Mohtarrudin2, Siti Farah Md Tohid1and Zainul Amiruddin Zakaria1,3,* The study was designed to assess the acute toxicity and anti-inflammatory potential of methanolic extract of Muntingia calabura L. (MEMC) in in vivo models. Bawa K, 1973. In this study, the leaves were prepared as MEMCL and subjected to ethanol- and indomethacin-induced gastric ulcers wherein in the former assay the doses of 25, 50, 100, 250, and 500 mg/ kg were used while in the later assay, the doses of 100, 250, ad 500 mg/kg were used. (6)(7) Muntingia calabura leaves extract exhibited significant pharmacological effects such as Muntingia calabura L. (family Elaeocarpaceae) has been traditionally used to relieve various pain-related ailments. Glycation and production of free radicals become important mechanisms underlying skin aging. The results conclude that the leaf infusion of M. calabura is … Anti-inflammatory Activity of Muntingia calabura Fruits Kathirvel Preethi,* Paramasivam Premasudha, Kittusamy Keerthana Department of Microbial Biotechnology, Bharathiar University, Coimbatore – 641 046 A B S t r A c t Muntingia calabura, the sole species in the genus Muntingia, is a flowering plant, that belongs to Elaeocarpaceae family. Background: Muntingia calabura (Elaecoparceae) is a medicinal plant traditionally used, particularly, by the Peruvian people to alleviate headache and cold, pain associated with gastric ulcers or to reduce the prostate gland swelling. The objects in this study were 30 male Wistar strain rats aged 2-3 months with a weight of 180-200 … The in vitro antiproliferative and antioxidant activities of the aqueous, chloroform and methanol extracts of Muntingia calabura leaves were determined in the present study. The leaves possess antinociceptive, anti-inflammatory and antipyretic activities [7]. Following the recent establishment of antinociceptive activity of M. calabura leaf, the present study was performed The present study aimed to determine the antinociceptive activity of methanol extract of M. calabura leaves (MEMC) and to elucidate the possible mechanism of antinociception involved. Journal of King Saud University-Science, 25(1), 83-89. Muntingia calabura is widely cultivated and has become one of the common roadside trees in Indonesia. Based on previous research, M. calabura leaves was known to contain flavonoid compounds, tannins, triterpenoids, saponins, and polyphenols that showed antioxidant activity. The leaf infusion of M. calabura at a concentration of 6% significantly inhibited EHI and AWM, higher than the negative control (P<0,05). Conclusion: Muntingia calabura possesses remarkable medicinal value, which warrants further and in-depth studies. The timbers are lightweight, durable and used in carpentry. Abstract. The leaves and fruits were studied for its phytochemical analysis both qualitatively and quantitatively and also for its behavior with aqueous extract powders, fluorescence, nutrients. Citation: Ibrahim IAA, Abdulla MA, Abdelwahab SI, Al-Bayaty F, Majid NA (2012) Leaves Extract of Muntingia Calabura Protects Against Gastric Ulcer Induced by Ethanol in Sprague-Dawley Rats. Muntingia calabura, commonly known as Jamaican cherry, is a plant species belonging to the family Muntingiaceae with variety of traditional uses. 2020; :1-13 (ISSN: 1532-7914). The leaves are alternate, distichous, oblong or lanceolate, 4–15 cm long and 1–6 cm wide, with toothed margin and covered in short hairs. (11) Antioxidants are substances that can inhibit The fruits of Muntingia calabura have antioxidant property [8]. Anti-inflammatory Activity: N. Jisha et al., (2019) published a research study on the anti-inflammatory potential of Muntingia calabura leaves methanol extract on female Wistar rats. Therefore, this review paper is presented to help guide researchers to plan their future studies related to this plant in the hope of isolating potential leads for future drug development. Inflammation is one of the warning signs of conditions like arthritis, certain … They subjected the test extract for toxicity studies, and the reports revealed that no symptoms of toxicity observed up to a dosage of 2000 mg/kg body weight. Our recent work encompasses the phytochemical profile and antioxidant activity to authenticate the medicinal properties of … There were no abnormal signs, behavioural changes, body weight changes, or. Muntingia calabura is one of the many species from the family Muntingiaceae used in folk medicine throughout the world. Various parts of M. calabura such as leaves, barks, flowers, and roots have The stem of Muntingia calabura was studied in the present study for its phytochemical analysis both qualitatively and … Jamaica cherry scientifically known as Muntingia calabura is a fast-growing small evergreen belong to genus Muntingia L. (muntingia) of the Elaeocarpaceae (Elaeocarpus family). ETHNOPHARMACOLOGICAL RELEVANCE: In traditional medicine, the leaves, flowers, barks and roots of Muntingia calabura L. (Muntingiaceae) have been employed as a treatment for various ailments including dyspepsia and to relieve pain caused by gastritis and peptic ulcer disease. 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